MORGANTOWN, W.Va. - Oklahoma used a 21-point, first-quarter scoring barrage to defeat 10^th-ranked West Virginia, 56-28, Saturday night at Milan Puskar Stadium.

The Sooners turned four Mountaineer turnovers into 27 points in handing WVU its most lopsided defeat of the season.

"Disappointing game tonight, disappointing for our fan base and disappointing for everyone," West Virginia coach Dana Holgorsen said. "We didn't get the job done. When you play a good football team you can't make the amount of mistakes that we made."

OU's talented running back tandem of Samaje Perine and Joe Mixon combined to rush for 307 yards - 160 of those coming from Perine - and quarterback Baker Mayfield passed for 169 yards and two touchdowns while running for two more scores to keep Oklahoma's slim college football playoff hopes alive.

OU, after dropping two of its first three games of the season, has now won eight straight and is 9-2/8-0 with the Bedlam Series against Oklahoma State remaining in two weeks for the Big 12 championship.

West Virginia (8-2, 5-2) turned the ball over four times - three coming on fumbles - committed seven penalties for 91 yards and couldn't slow down the nation's third-ranked offense.

"I don't know how many times we are going to fumble inside the 5-yard line and think it's okay," Holgorsen said. "You get down there you've got to score."

The night turned sour for West Virginia soon after the game's opening possession when the Sooners were forced to punt from their own 38.

Austin Seibert's punt into a driving snowstorm was mishandled by Gary Jennings at the West Virginia 34 and Oklahoma's Sam Grant recovered the ball there.

Four Mixon runs advanced the football 32 yards, Dede Westbrook got another yard on a wide receiver reverse and Perine carried it the remaining two yards for Oklahoma's first touchdown.

The Sooners' second score came quickly following a three-and-out possession by the Mountaineers when Westbrook took a third-down Mayfield pass at the line of scrimmage, broke free and raced 75 yards for a touchdown.

Another ineffective Mountaineer offensive possession gave the ball right back to OU at its own 22, and the Sooners marched 78 yards for their third score, this one a Mayfield 5-yard pass to Jeffery Mead.

All but 25 of OU's yards on the drive came on the ground courtesy of Mixon and Perine.

Oklahoma's fourth touchdown followed West Virginia's second turnover - a Justin Crawford fumble at the Sooner 4 after he had made long runs of 29 and 36 yards to get there.

OU marched 96 yards in eight plays - mostly on the ground once again - to reach paydirt when Mixon bulled in from the 5. Seibert's conversion made it 28-0, Oklahoma.

At this point, many of the 57,645 who braved tonight's frigid conditions headed to the exits.

"It was tough conditions but they handled it better than we did," Holgorsen said.

Another West Virginia turnover, a Skyler Howard fumble, gave OU the ball at its own 3. The Sooners drove 97 yards this time - aided by personal foul penalties on Christian Brown and Noble Nwachukwu for 30 yards - to score its fifth touchdown, a Perine nine-yard run. Seibert's conversion was no good this time.

West Virginia finally got into the end zone right before the end of the first half when Howard hit Jovon Durante on a 20-yard scoring toss.

West Virginia's opening possession of the third quarter appeared promising, the Mountaineers traveling to the Oklahoma 34, but it ended abruptly when linebacker Jordan Evans stepped in front of a fourth-down Howard pass at the 20, picked up a wall of blockers at midfield and raced 80 yards for a touchdown.

A Rasul Douglas interception - his seventh of the season - set up West Virginia's second touchdown, a Howard 6-yard run. Crawford once again did most of the work, running 45 yards to the OU 18 to set up Howard's score.

OU's porous defense, which gave up big chunks of yardage all evening, kept those still left in the stadium somewhat interested in the game.

Shelton Gibson ran right past Oklahoma corner Jordan Thomas for a 61-yard gainer to the OU 18, and Howard eventually completed the drive with his second touchdown run, this one from nine yards, making the score 41-21.

Again, West Virginia was able to get behind Oklahoma's secondary, this time Ka'Raun White running open for a 37-yard touchdown with 10:06 remaining to make it a two-possession game, 41-28.

Here Oklahoma's offense, asleep for most of the second half, woke up to drive 65 yards in 11 plays, Mayfield converting two third-down passes before getting in from the one.

Mayfield's two-point conversion pass to Mark Andrews was successful, making the score 49-28.  

Soon after Mayfield's TD, the snow began falling once again, and the Sooner defense stopped West Virginia on fourth down to take posession at the WVU 28.

Perine ran to the WVU seven, then to the five and then to the three before Abdul Adams was stopped at the one. On fouth down, Mayfield pulled the football out of Adams' arms at the three. A horde of Mountaineer defenders swarmed Adams, and Mayfield walked in for OU's 55^th point. Seibert's conversion completed the scoring.

On the game's final possession, Crawford ran 45 yards to the OU 29, giving the junior 331 yards - 13 shy of the school record of 344 established by Tavon Austin against Oklahoma in 2012.

Instead of handing the ball to Crawford a 25^th time, Howard tried a pass on the final play of the game and it fell to the ground as time ran out.

Crawford was playing in place of injured starting running back Kennedy McKoy, who hurt his shoulder on West Virginia's first offensive play of the game.

Howard completed 12 of 27 passes for 191 yards and two touchdowns, four of those going to White for 58 yards.

West Virginia actually outgained Oklahoma, 579-485, but most of those yards came with the Sooners comfortably ahead.

West Virginia plays its final regular season road game of the year at improving Iowa State next Saturday. The Cyclones defeated Texas Tech earlier today, 66-10.